NIST 800-53 compliance refers to adherence to the security and privacy controls outlined in the National Institute of Standards and Technology (NIST) Special Publication 800-53, titled Security and Privacy Controls for Information Systems and Organizations. This control catalog provides a comprehensive set of technical and administrative safeguards designed to protect the confidentiality, integrity, and availability of federal information systems and other critical assets.
Originally developed for U.S. federal agencies and their contractors, NIST 800-53 is increasingly adopted across sectors such as critical infrastructure, energy, finance, and healthcare as a baseline for cybersecurity best practices. The publication defines a structured control framework, organized into 20 control families, including:
Access control is a central focus of several IEC 62443 components:
Controls such as AC-2, AC-17, AU-2, and SI-4 directly address access governance, remote access security, and session auditing, areas where noncompliance can result in data breaches or regulatory penalties. NIST 800-53 also provides a foundation for other frameworks, including FedRAMP, FISMA, and CMMC.
Xona helps organizations meet NIST 800-53 technical access control and auditing requirements by enforcing secure, policy-based remote access to critical systems, without exposing internal credentials or networks. Key capabilities that align with NIST 800-53 controls include:
Xona’s access gateway creates a clean separation between users and target systems through protocol isolation and browser-based access, making it easier for security teams to apply and demonstrate control alignment with NIST 800-53 requirements across IT and OT environments.